Mississippi Roast, also known as Slow Cooker Pepperoncini Pot Roast, is a dish that features a beef roast cooked in a slow cooker with pepperoncini peppers, butter, and various seasonings. While the benefits of this specific dish may depend on the quality of ingredients used, as well as portion size and individual dietary needs, there are some potential general benefits to eating beef and peppers.

Beef is a good source of protein, which is essential for building and repairing tissues in the body. It also contains iron, which is important for the formation of red blood cells. Additionally, beef can be a source of other key nutrients like zinc, vitamin B12, and selenium.

Pepperoncini peppers can also provide some health benefits. They are low in calories and high in vitamin C, which supports immune function, wound healing, and collagen production. Some research suggests that capsaicin, the compound that gives peppers their spiciness, may have anti-inflammatory and pain-relieving properties.

However, it’s worth noting that Mississippi Roast typically contains a significant amount of butter, which can contribute to a high calorie and saturated fat content. Therefore, moderation and balance are important when incorporating this dish into your diet.

Mississippi Roast (Slow Cooker Pepperoncini Pot Roast)

Prep Time 10 minutes
Cook Time 8 hours
Total Time 8 hours 10 minutes
Course Main Course
Cuisine American
Servings 6 people
Calories 537 kcal


  • To make Mississippi Roast, you will need a few basic kitchen equipment such as:
  • A slow cooker: The main equipment you will need is a slow cooker or crockpot to cook the roast. This allows the meat to cook slowly and become tender and flavorful.
  • Meat thermometer A meat thermometer is essential to ensure that the roast is cooked to the correct temperature. The internal temperature of the roast should reach 145°F (63°C) for medium-rare and 160°F (71°C) for medium.
  • Cutting board You'll need a cutting board to prepare the roast before cooking it in the slow cooker.
  • Sharp knife A sharp knife will make it easier to trim any excess fat from the roast and to slice it after it's cooked.
  • Tongs or forks: You will also need tongs or forks to transfer the roast to and from the slow cooker and to shred the meat once it's cooked.
  • Measuring cups and spoons You will need measuring cups and spoons to accurately measure the ingredients such as beef broth, butter, pepperoncini peppers, etc.
  • Overall, these are the basic equipment you will need to make Mississippi Roast.


  • (4 pound)  beef chuck roast
  • ¼  cup  butter
  •  pepperoncini peppers
  • (1 ounce) packet ranch dressing mix
  • (1 ounce) packet dry au jus mix


  • Step 1
    Place broil in a sluggish cooker. Structure a pocket in the highest point of the meal and spot spread, pepperoncini peppers, farm dressing blend, and in its natural juices blend in the pocket.
  • Step 2
    Cook on Low for 8 hours.


Substitute beef round or beef brisket for the beef chuck, if desired.
Keyword Pepperoncini